Article

A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniae

2025-09-02

Abstract excerpt

Streptococcus pneumoniae is a pathogenic bacterium capable of entering a cellular differentiation state, called competence, which enables it to acquire new genetic functions by natural transformation, as well as physiological functions such as tolerance to a number of antibiotics. The transition to this state is regulated by various environmental or intracellular signals that converge on the comCDE operon, which...

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Literature Corpus work: 347a9b19-107d-540f-ae17-a7a68133b43e
DOI: 10.1101/2025.09.02.673660

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