Article
Identification of single nucleotide polymorphisms from the transcriptome of an organism with a whole genome duplication.
BMC bioinformatics - 16 Nov 2013
Christensen Kris A, Brunelli Joseph P, Lambert Matthew J, DeKoning Jenefer, Phillips Ruth B, Thorgaard Gary H
Abstract excerpt
BACKGROUND: The common ancestor of salmonid fishes, including rainbow trout (Oncorhynchus mykiss), experienced a whole genome duplication between 20 and 100 million years ago, and many of the duplicated genes have been retained in the trout genome. This retention complicates efforts to detect allelic variation in salmonid fishes. Specifically, single nucleotide polymorphism (SNP) detection is problematic because...
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