Article
Transcriptome sequencing and high-resolution melt analysis advance single nucleotide polymorphism discovery in duplicated salmonids.
Molecular ecology resources - 1 Mar 2011
Seeb J E, Pascal C E, Grau E D, Seeb L W, Templin W D, Harkins T, Roberts S B
Abstract excerpt
Until recently, single nucleotide polymorphism (SNP) discovery in nonmodel organisms faced many challenges, often depending upon a targeted-gene approach and Sanger sequencing of many individuals. The advent of next-generation sequencing technologies has dramatically improved discovery, but validating and testing SNPs for use in population studies remain labour intensive. Here, we detail a SNP discovery and...
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