Article
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyploid species.
BMC bioinformatics - 9 Oct 2006
Tang Jifeng, Vosman Ben, Voorrips Roeland E, van der Linden C Gerard, Leunissen Jack A M
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use of the large number of sequences present in public databases (in most cases as expressed sequence tags (ESTs)) and are considered to be faster and more cost-effective than experimental procedures. A major challenge in computational SNP...
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