Article
Methylation of a CpG site near the ALDH1A2 gene is associated with loss of control over drinking and related phenotypes.
Alcoholism, clinical and experimental research - 1 Mar 2014
Harlaar Nicole, Bryan Angela D, Thayer Rachel E, Karoly Hollis C, Oien Niles, Hutchison Kent E
Abstract excerpt
BACKGROUND: The pathophysiology of alcohol use disorders (AUDs) may be influenced by epigenetics processes such as DNA methylation, but the identification of DNA methylation patterns associated with AUDs has largely been limited to a handful of candidate genes. METHODS: Participants were hazardous drinkers from the local community (n = 309). All participants completed a baseline clinical interview in which they...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.