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Article

Emerging Role of Epigenetic Mechanisms in Alcohol Addiction

23 Jan 2017

Abstract excerpt

Alcohol use disorder (AUD) is a complex brain disorder with an array of persistent behavioral and neurochemical manifestations. Both genetic and environmental factors are known to contribute to the development of AUD, and recent studies on alcohol exposure and subsequent changes in gene expression suggest the importance of epigenetic mechanisms. In particular, histone modifications and DNA methylation have...

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PMID: 28111764
DOI: 10.1111/acer.13338

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