Article
TNFRSF10A-LOC389641 rs13278062 but not REST-C4orf14-POLR2B-IGFBP7 rs1713985 was found associated with age-related macular degeneration in a Chinese population.
Investigative ophthalmology & visual science - 17 Dec 2013
Sun Yaoyao, Li Shanshan, Li Haiping, Yang Fei, Bai Yujing, Zhao Min, Guo Jing, Zhao Mingwei, Zhou Peng, Khor Chiea Chuen, Huang Lvzhen, Li Xiaoxin
Abstract excerpt
PURPOSE: To reassess the association between TNFRSF10-LOC389641 rs13278062 and REST-C4orf14-POLR2B-IGFBP7 rs1713985 with the risk of AMD in a Chinese case-control collection. METHODS: The primary study consisted of 1826 subjects, including 1226 controls, 300 cases with nAMD, and 300 cases with PCV. Genomic DNA was extracted from venous blood leukocytes. The allelic variants of rs13278062 and rs1713985 were...
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