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Article

rs4711751 and rs1999930 are not associated with neovascular age-related macular degeneration or polypoidal choroidal vasculopathy in the Chinese population.

Ophthalmic research - 1 Jan 2014

Huang Lvzhen, Li Mingwu, Ma Xiaoyun, Li Yingjie, Zhang Chunfang, Sun Yaoyao, Bai Yujing, Wang Bin, Yu Wenzhen, Zhao Mingwei, Khor Chiea Chuen, Li Xiaoxin

Abstract excerpt

PURPOSE: rs1999930 and rs4711751 have recently been identified as novel variants associated with advanced age-related macular degeneration (AMD) in populations of European ancestry. We aimed to investigate whether these two single nucleotide polymorphisms (SNPs) were associated with neovascular AMD (nAMD) or with polypoidal choroidal vasculopathy (PCV), a variant of AMD in Asians, using a Chinese case-control...

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PMID: 25228097
DOI: 10.1159/000362763

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