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Article

Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit.

Critical care medicine - 1 Jan 2009

Henckaerts Liesbet, Nielsen Kaspar R, Steffensen Rudi, Van Steen Kristel, Mathieu Chantal, Giulietti Annapaula, Wouters Pieter J, Milants Ilse, Vanhorebeek Ilse, Langouche Lies, Vermeire Séverine, Rutgeerts Paul, Thiel Steffen, Wilmer Alexander, Hansen Troels Krarup, Van den Berghe Greet

Abstract excerpt

OBJECTIVE: Critically ill patients are at risk of sepsis, organ failure, and death. Studying the impact of genetic determinants may improve our understanding of the pathophysiology and allow identification of patients who would benefit from specific treatments. Our aim was to study the influence of single nucleotide polymorphisms in selected genes involved in innate immunity on the development of bacteremia or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19050632
DOI: 10.1097/CCM.0b013e31819263d8

Genes

MASP2
NOD2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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