Article
High-throughput molecular genotyping for small biopsy samples in advanced non-small cell lung cancer patients.
Anticancer research - 1 Nov 2013
Maeng Chi Hoon, Lee Ho Yun, Kim Young Wook, Choi Moon Ki, Hong Jung Yong, Jung Hyun Ae, Lee Kyung Soo, Kim Hojoong, Kwon O Jung, Sun Jong-Mu, Ahn Jin Seok, Park Keunchil, Um Sang-Won, Ahn Myung-Ju
Abstract excerpt
BACKGROUND: Despite the key role of mutational analysis in targeted therapy, the difficulty in acquisition of adequate tumor tissues for molecular genotyping in advanced non-small cell lung cancer (NSCLC) has led to the need for a fast and efficient method for detecting genetic alterations for targeted therapy. PATIENTS AND METHODS: We analyzed tissue specimens of advanced NSCLC. A mass spectrometry-based assay...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
