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Article

The introduction of systematic genomic testing for patients with non-small-cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Dec 2012

Cardarella Stephanie, Ortiz Taylor M, Joshi Victoria A, Butaney Mohit, Jackman David M, Kwiatkowski David J, Yeap Beow Y, Jänne Pasi A, Lindeman Neal I, Johnson Bruce E

Abstract excerpt

BACKGROUND: Genomic testing to identify driver mutations that enable targeted therapy is emerging for patients with non-small-cell lung cancer (NSCLC). We report the implementation of systematic prospective genotyping for somatic alterations in BRAF, PIK3CA, HER2, and ALK, in addition to EGFR and KRAS, in NSCLC patients at the Dana-Farber Cancer Institute. METHODS: Patients with NSCLC were prospectively referred...

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Source

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Identifiers

PMID: 23154547
DOI: 10.1097/JTO.0b013e3182745bcb
PMCID: PMC3500523

Genes

ALK
BRAF
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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