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Article

Novel association between CD74 polymorphisms and hematologic toxicity in patients with NSCLC after platinum-based chemotherapy.

Clinical lung cancer - 1 Jan 2014

Tan Xiaoming, Wu Qihan, Cai Yanyan, Zhao Xueying, Wang Shingming, Gao Zhiqiang, Yang Yang, Li Xiaoying, Qian Ji, Wang Jiucun, Su Bo, Chen Hongyan, Han Baohui, Jiang Gening, Lu Daru

Abstract excerpt

BACKGROUND: Platinum-based chemotherapy regimens can cause DNA damage. Macrophage migration inhibitory factor (MIF) plays an important role in the regulation of the cell cycle by either controlling the activity of the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex or activating its receptor, CD74. PATIENTS AND METHODS: We used a pathway-based approach to investigate the association between genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24220096
DOI: 10.1016/j.cllc.2013.08.006

Genes

MIF
SKP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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