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Article

Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC.

Clinical lung cancer - 1 Sept 2015

Qian Ji, Liu Hongliang, Gu Shaohua, Wu Qihan, Zhao Xueying, Wu Wenting, Wang Haijian, Wang Jiucun, Chen Hongyan, Zhang Wei, Wei Qingyi, Jin Li, Lu Daru

Abstract excerpt

INTRODUCTION: Platinum agents can cause the formation of DNA adducts and induce apoptosis to eliminate tumor cells. The aim of the present study was to investigate the influence of genetic variants of MDM2 on chemotherapy-related toxicities and clinical outcomes in patients with advanced non-smal...

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Source

Identifiers

PMID: 25818095
DOI: 10.1016/j.cllc.2015.02.001

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25818095-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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