Article
Genetic variants on 17q21 are associated with ankylosing spondylitis susceptibility and severity in a Chinese Han population.
Scandinavian journal of rheumatology - 1 Jan 2013
Qiu R, Zhang H, Zhao H, Li J, Guo C, Gong Y, Liu Q
Abstract excerpt
OBJECTIVES: The aim of this study was to test whether orosomucoid like 3 (ORMDL3) and 17q21 variants are associated with susceptibility to ankylosing spondylitis (AS) in a Chinese population. METHOD: A total of 753 unrelated AS patients and 1120 ethnically matched healthy controls were recruited. Seven single nucleotide polymorphisms (SNPs: rs7216389, rs12603332, rs12936231, rs9303277, rs11557467, , and...
