Article
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
Journal of clinical laboratory analysis - 1 Nov 2013
Kucukhuseyin Ozlem, Kurnaz Ozlem, Akadam-Teker A Basak, Isbir Turgay, Bugra Zehra, Ozturk Oguz, Yilmaz-Aydogan Hulya
Abstract excerpt
BACKGROUND: The aim of this study is to investigate whether methylenetetrahydrofolate reductase (MTHFR) C677T mutation is associated with the development of hyperlipoproteinemia and obesity in coronary heart disease (CHD). METHODS: This study was carried out in 82 diabetic and 112 nondiabetic patients with CHD and in 138 CHD-free healthy controls. Polymerase chain reaction-restriction fragment length polymorphism...
Topics
- Adult
- Aged
- Body Mass Index
- Coronary Disease
- Diabetes Complications
- Female
- Genetic Association Studies
- Genotype
- Humans
- Lipids
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged