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Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus.

Clinical biochemistry - 1 Dec 2011

Chang Yih-Hsin, Fu Wen-Mei, Wu Yu-Hui, Yeh Chih-Jung, Huang Chien-Ning, Shiau Ming-Yuh

Abstract excerpt

OBJECTIVES: Deficiency and/or decreased activity of methyltetrahydrofolate reductase (MTHFR) resulted from MTHFR variants are associated with hyperhomocysteinemia, an independent risk factor for vasculopathies in diabetic patients. The aim of this study was to examine MTHFR genotypes between healthy and type 2 diabetes mellitus (T2DM) subjects. DESIGN AND METHODS: MTHFR C677T and A1298C genotypes were analyzed in...

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Source

Identifiers

PMID: 22008727
DOI: 10.1016/j.clinbiochem.2011.09.020

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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