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Article

MTHFR C677T polymorphism affects normotensive diastolic blood pressure independently of blood lipids.

American journal of hypertension - 1 Mar 2015

Heifetz Eliyahu M, Birk Ruth Z

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism was found to be associated with hypertension. High blood pressure (BP) is a major risk factor for cardiovascular disease, gestational hypertension, and high-risk pregnancy. BP is a complex trait strongly associated with blood lipid parameters. However, studies of the effect of MTHFR C677T polymorphism on BP levels independently of blood...

Topics

Adult
Age Factors
Blood Pressure
Body Mass Index
Diastole
Female
Folic Acid
Gene Frequency
Genotype
Homocysteine
Humans
Lipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methylenetetrahydrofolate Reductase (NADPH2)

Middle Aged

Polymorphism, Single Nucleotide

Young Adult

Source

Identifiers

PMID: 25165067
DOI: 10.1093/ajh/hpu152

Genes

MTHFR
DBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25165067-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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MTHFR C677T polymorphism affects normotensive diastolic blood pressure independently of blood lipids.PMID 25165067Read ↗

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