Article
Methylenetetrahydrofolate reductase polymorphism, type II diabetes mellitus, coronary artery disease, and essential hypertension in the Czech population.
Molecular genetics and metabolism - 1 Jun 2001
Benes P, Kanková K, Muzík J, Groch L, Benedík J, Elbl L, Izakovicová-Hollá L, Vasků A, Znojil V, Vácha J
Abstract excerpt
Increased plasma concentrations of homocysteine have been found in patients with coronary artery disease (CAD) and essential hypertension (EH) and in patients with diabetic complications. The 677C/T methylenetetrahydrofolate reductase (MTHFR) gene polymorphism is related to the MTHFR enzyme activity and to the plasma homocysteine concentration. This study was designed to investigate an association of this...
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