Article
Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach.
American journal of epidemiology - 1 Feb 2014
O'Brien Katie M, Cole Stephen R, Poole Charles, Bensen Jeannette T, Herring Amy H, Engel Lawrence S, Millikan Robert C
Abstract excerpt
Genome-wide association studies (GWAS) and candidate gene analyses have led to the discovery of several dozen genetic polymorphisms associated with breast cancer susceptibility, many of which are considered well-established risk factors for the disease. Despite attempts to replicate these same variant-disease associations in African Americans, the evaluable populations are often too small to produce precise or...
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