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Article

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi.

Antimicrobial agents and chemotherapy - 1 Jan 2014

Dickinson Laura, Chaponda Masautso, Carr Daniel F, van Oosterhout Joep J, Kumwenda Johnstone, Lalloo David G, Pirmohamed Munir, Heyderman Robert S, Khoo Saye H

Abstract excerpt

We modeled nevirapine (NVP) pharmacokinetics in HIV-infected Malawian patients to assess the relationship between drug exposure and patient characteristics, genetic polymorphisms, and development of hypersensitivity reaction (HSR). One thousand one hundred seventeen patients were prospectively re...

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Identifiers

PMID: 24217698
DOI: 10.1128/AAC.02069-13
PMCID: PMC3910846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24217698-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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