Article
High glucose concentration does not modulate the formation of arterial medial calcification in experimental uremic rats.
Journal of vascular research - 1 Jan 2013
Yoshida Tadashi, Yamashita Maho, Horimai Chihiro, Hayashi Matsuhiko
Abstract excerpt
High phosphate-induced phenotypic switching of smooth muscle cells (SMCs) into osteogenic cells is critical for the formation of arterial medial calcification in chronic kidney disease. Because vascular calcification is also prevalent in type 2 diabetes, we examined whether glucose concentration affects high phosphate-induced SMC phenotypic switching and calcification. First, the formation of arterial medial...
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