Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution.

doi:10.1016/j.jad.2013.10.027

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Article

Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution.

Journal of affective disorders - 1 Feb 2014

Ferentinos Panagiotis, Rivera Margarita, Ising Marcus, Spain Sarah L, Cohen-Woods Sarah, Butler Amy W, Craddock Nicholas, Owen Michael J, Korszun Ania, Jones Lisa, Jones Ian, Gill Michael, Rice John P, Maier Wolfgang, Mors Ole, Rietschel Marcella, Lucae Susanne, Binder Elisabeth B, Preisig Martin, Tozzi Federica, Muglia Pierandrea, Breen Gerome, Craig Ian W, Farmer Anne E, Müller-Myhsok Bertram, McGuffin Peter, Lewis Cathryn M

Abstract excerpt

BACKGROUND: Highly recurrent major depressive disorder (MDD) has reportedly increased risk of shifting to bipolar disorder; high recurrence frequency has, therefore, featured as evidence of 'soft bipolarity'. We aimed to investigate the genetic underpinnings of total depressive episode count in recurrent MDD. METHODS: Our primary sample included 1966 MDD cases with negative family history of bipolar disorder from...

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PMID: 24215895
DOI: 10.1016/j.jad.2013.10.027

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MAGI1
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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