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Article

O-GlcNAcylation of cofilin promotes breast cancer cell invasion.

The Journal of biological chemistry - 20 Dec 2013

Huang Xun, Pan Qiuming, Sun Danni, Chen Wei, Shen Aijun, Huang Min, Ding Jian, Geng Meiyu

Abstract excerpt

O-GlcNAcylation is a post-translational modification that regulates a broad range of nuclear and cytoplasmic proteins and is emerging as a key regulator of various biological processes. Previous studies have shown that increased levels of global O-GlcNAcylation and O-GlcNAc transferase (OGT) are linked to the incidence of metastasis in breast cancer patients, but the molecular basis behind this is not fully...

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Source

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Identifiers

PMID: 24214978
DOI: 10.1074/jbc.M113.495713
PMCID: PMC3868755

Genes

OGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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