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Article

Pharmacogenetics: Using Genetic Information to Guide Drug Therapy.

American family physician - 1 Oct 2015

Chang Ku-Lang, Weitzel Kristin, Schmidt Siegfried

Abstract excerpt

Clinical pharmacogenetics, the use of genetic data to guide drug therapy decisions, is beginning to be used for medications commonly prescribed by family physicians. However, clinicians are largely unfamiliar with principles supporting clinical use of this type of data. For example, genetic variability in the cytochrome P450 2D6 drug metabolizing enzyme can alter the clinical effects of some opioid analgesics...

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PMID: 26447442
PMCID: PMC4729205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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