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Article

HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity.

Cell reports - 14 Nov 2013

Usami Yoshiko, Göttlinger Heinrich

Abstract excerpt

HIV-1 Nef and the unrelated murine leukemia virus glycoGag similarly enhance the infectivity of HIV-1 virions. We now show that the effects of Nef and glycoGag are similarly determined by variable regions of HIV-1 gp120 that control Env trimer association and neutralization sensitivity. Whereas n...

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Share to Amino Acid Sequence
Share to env Gene Products, Human Immunodeficiency Virus
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

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Share to nef Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 24209751
DOI: 10.1016/j.celrep.2013.09.028
PMCID: PMC3864691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24209751-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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