Article
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.
Molecular microbiology - 1 Nov 2003
Singh Ramandeep, Rao Vivek, Shakila H, Gupta Radhika, Khera Aparna, Dhar Neeraj, Singh Amit, Koul Anil, Singh Yogendra, Naseema M, Narayanan P R, Paramasivan C N, Ramanathan V D, Tyagi Anil K
Abstract excerpt
Protein tyrosine kinases and tyrosine phosphatases from several bacterial pathogens have been shown to act as virulence factors by modulating the phosphorylation and dephosphorylation of host proteins. The identification and characterization of two tyrosine phosphatases namely MptpA and MptpB fro...
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