Article
Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs.
Infection and immunity - 1 Aug 2003
Rousseau Cécile, Turner Oliver C, Rush Erik, Bordat Yann, Sirakova Tatiana D, Kolattukudy Pappachan E, Ritter Shannon, Orme Ian M, Gicquel Brigitte, Jackson Mary
Abstract excerpt
Lipids that are found only in the cell envelope of pathogenic mycobacteria, such as those containing multiple methyl-branched fatty acids, have long been thought to play a role in pathogenesis. Among these complex lipids, sulfolipids have been the most extensively studied over the last 50 years. The numerous biological effects exhibited by purified sulfolipids on phagocytic cells led to the idea that these...
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