Article
Dynamic tumor growth patterns in a novel murine model of colorectal cancer.
Cancer prevention research (Philadelphia, Pa.) - 1 Jan 2014
Paul Olson Terrah J, Hadac Jamie N, Sievers Chelsie K, Leystra Alyssa A, Deming Dustin A, Zahm Christopher D, Albrecht Dawn M, Nomura Alice, Nettekoven Laura A, Plesh Lauren K, Clipson Linda, Sullivan Ruth, Newton Michael A, Schelman William R, Halberg Richard B
Abstract excerpt
Colorectal cancer often arises from adenomatous colonic polyps. Polyps can grow and progress to cancer, but may also remain static in size, regress, or resolve. Predicting which polyps progress and which remain benign is difficult. We developed a novel long-lived murine model of colorectal cancer with tumors that can be followed by colonoscopy. Our aim was to assess whether these tumors have similar growth...
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