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Homogeneous Expansion of Human T-Regulatory Cells Via Tumor Necrosis Factor Receptor 2

6 Nov 2013

Abstract excerpt

T-regulatory cells (T(regs)) are a rare lymphocyte subtype that shows promise for treating infectious disease, allergy, graft-versus-host disease, autoimmunity, and asthma. Clinical applications of T(regs) have not been fully realized because standard methods of expansion ex vivo produce heterogeneous progeny consisting of mixed populations of CD4 + T cells. Heterogeneous progeny are risky for human clinical...

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PMID: 24193319
DOI: 10.1038/srep03153

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