Article
Characterization of subpopulation lacking both B-cell and plasma cell markers in Waldenstrom macroglobulinemia cell line.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 2014
Wada Naoki, Zhan Maosheng, Hori Yumiko, Honma Keiichiro, Ikeda Jun-ichiro, Morii Eiichi
Abstract excerpt
Cancer cells with tumorigenic potential are limited to a small population known as cancer-initiating cells (CICs). To date, CICs have not been identified in non-Hodgkin's lymphomas. Here, we investigated a candidate of CICs of an indolent non-Hodgkin's lymphoma, Waldenstrom macroglobulinemia (WM), using WM cell line MWCL-1. WM tumor expresses both B-cell and plasma cell markers, CD20 and CD138. When stained with...
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