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Article

Waldenström's macroglobulinemia: Two malignant clones in a monoclonal disease? Molecular background and clinical reflection.

European journal of haematology - 1 Dec 2017

Growková Kateřina, Kryukova Elena, Kufová Zuzana, Filipová Jana, Ševčíková Tereza, Říhová Lucie, Kaščák Michal, Kryukov Fedor, Hájek Roman

Abstract excerpt

Waldenström's macroglobulinemia (WM) is a complex disease characterized by apparent morphological heterogeneity within the malignant clonal cells representing a continuum of small lymphocytes, plasmacytoid lymphocytes, and plasma cells. At the molecular level, the neoplastic B cell-derived clone has undergone somatic hypermutation, but not isotype switching, and retains the capability of plasmacytic...

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PMID: 28886236
DOI: 10.1111/ejh.12959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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