Article
The immune-enhancing effect of the Cronobacter sakazakii ES2 phage results in the activation of nuclear factor-κB and dendritic cell maturation via the activation of IL-12p40 in the mouse bone marrow.
Immunology letters - 1 Jan 2000
An Tae-Woo, Kim Sun-Joong, Lee Young-Duck, Park Jong-Hyun, Chang Hyo-Ihl
Abstract excerpt
The bacteriophage ES2 is a virus for bacterial host cells. Unlike other phages that are known for their therapeutic effects, the ES2 phage has never been clearly examined as a therapeutic agent. To systematically and conclusively evaluate its therapeutic efficacy, the expression of the surface markers CD86, CD40, and MHCII, the production of the proinflammatory cytokines IL-6, IL-1α, IL-1β, and TNF-α, and the...
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