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Contribution of the Immune Response to Phage Therapy

23 Apr 2018

Abstract excerpt

Therapeutic phages are being employed for vaccination and treatment of cancer and bacterial infections. Their natural immunogenicity triggers intertwined interactions with innate and adaptive immune cells that might influence therapy. Phage- and bactierial-derived pathogen-associated molecular patterns released after bacterial lysis have been proposed to stimulate local innate immune responses, which could...

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PMID: 29685950
DOI: 10.4049/jimmunol.1701745

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