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Article

Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids.

Journal of psychosomatic research - 1 Nov 2013

Lotrich Francis E, Sears Barry, McNamara Robert K

Abstract excerpt

OBJECTIVE: Anger worsens in some patients during interferon-alpha (IFN-α) therapy. Elevated anger has also been associated with lower long-chain omega-3 (LCn-3) fatty acid levels. We examined whether fatty acids could influence vulnerability to anger during IFN-α exposure. METHODS: Plasma arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) levels were determined prior to IFN-α...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24182638
DOI: 10.1016/j.jpsychores.2013.07.012
PMCID: PMC3817416

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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