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Article

Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study.

Translational psychiatry - 29 Aug 2017

Berger M E, Smesny S, Kim S-W, Davey C G, Rice S, Sarnyai Z, Schlögelhofer M, Schäfer M R, Berk M, McGorry P D, Amminger G P

Abstract excerpt

While cross-sectional studies suggest that patients with mood disorders have a higher ratio of omega-6 to omega-3 polyunsaturated fatty acids (PUFAs) and lower levels of omega-3 PUFAs, it is unknown if a high n-6/3 ratio indicates vulnerability for depression. We tested this hypothesis in a 7-year follow-up study of young individuals with an ultra-high risk (UHR) phenotype. We conducted a secondary analysis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28850110
DOI: 10.1038/tp.2017.190
PMCID: PMC5611753

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