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Article

PKCι maintains a tumor-initiating cell phenotype that is required for ovarian tumorigenesis.

Molecular cancer research : MCR - 1 Dec 2013

Wang Yin, Hill Kristen S, Fields Alan P

Abstract excerpt

UNLABELLED: Protein kinase Cι (PKCι) has oncogenic potential and is an attractive therapeutic target for treatment of lung cancer, particularly those tumors that express elevated PKCι. However, whether PKCι is a viable target in ovarian cancer is unknown, and virtually nothing is known about the mechanism by which PKCι drives ovarian tumorigenesis. Here, it is demonstrated that PKCι maintains a tumor-initiating...

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Identifiers

PMID: 24174471
DOI: 10.1158/1541-7786.MCR-13-0371-T
PMCID: PMC3888959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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