Article

Requirement for PKC Epsilon in Kras-Driven Lung Tumorigenesis

2020-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Non-small cell lung cancer (NSCLC), the most frequent subtype of lung cancer, remains a highly lethal malignancy and one of the leading causes of cancer deaths worldwide. Mutant KRAS is the prevailing oncogenic driver of lung adenocarcinoma, the most common histological form of NSCLC. In this study, we examined the role of PKCε, an oncogenic kinase highly expressed in NSCLC and other cancers, in...

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Literature Corpus work: 8d3f9880-255f-581d-9524-a1b38043342f
DOI: 10.1101/2020.06.26.173690

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