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Article

Differences in DNA methylation by extent of breast cancer family history in unaffected women.

Epigenetics - 1 Feb 2014

Delgado-Cruzata Lissette, Wu Hui-Chen, Liao Yuyan, Santella Regina M, Terry Mary Beth

Abstract excerpt

Breast cancer clusters within families but genetic factors identified to date explain only a portion of this clustering. Lower global DNA methylation in white blood cells (WBC) has been associated with increased breast cancer risk. We examined whether WBC DNA methylation varies by extent of breast cancer family history in unaffected women from high-risk breast cancer families. We evaluated DNA methylation levels...

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Identifiers

PMID: 24172832
DOI: 10.4161/epi.26880
PMCID: PMC3962534

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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