Article
Biologic Mechanisms of Macrophage Phenotypes Responding to Infection and the Novel Therapies to Moderate Inflammation.
International journal of molecular sciences - 6 May 2023
Ni Renhao, Jiang Lingjing, Zhang Chaohai, Liu Mujie, Luo Yang, Hu Zeming, Mou Xianbo, Zhu Yabin
Abstract excerpt
Pro-inflammatory and anti-inflammatory types are the main phenotypes of the macrophage, which are commonly notified as M1 and M2, respectively. The alteration of macrophage phenotypes and the progression of inflammation are intimately associated; both phenotypes usually coexist throughout the whole inflammation stage, involving the transduction of intracellular signals and the secretion of extracellular...
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