Article
Human Bone Marrow Mesenchymal Stem Cells Promote the M2 Phenotype in Macrophages Derived from STEMI Patients.
International journal of molecular sciences - 13 Nov 2023
Cortés-Morales Víctor Adrián, Vázquez-González Wendy Guadalupe, Montesinos Juan José, Moreno-Ruíz Luis, Salgado-Pastor Selene, Salinas-Arreola Pamela Michelle, Díaz-Duarte Karla, Chávez-Rueda Adriana Karina, Chávez-Sánchez Luis
Abstract excerpt
Acute ST-elevation myocardial infarction (STEMI) leads to myocardial injury or necrosis, and M1 macrophages play an important role in the inflammatory response. Bone marrow mesenchymal stem/stromal cells (BM-MSCs) are capable of modulating macrophage plasticity, principally due to their immunoregulatory capacity. In the present study, we analyzed the capacity of MSCs to modulate macrophages derived from monocytes...
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