APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

doi:10.1158/0008-5472.CAN-13-1753

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Article

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

Cancer research - 15 Dec 2013

Leonard Brandon, Hart Steven N, Burns Michael B, Carpenter Michael A, Temiz Nuri A, Rathore Anurag, Vogel Rachel I, Nikas Jason B, Law Emily K, Brown William L, Li Ying, Zhang Yuji, Maurer Matthew J, Oberg Ann L, Cunningham Julie M, Shridhar Viji, Bell Debra A, April Craig, Bentley David, Bibikova Marina, Cheetham R Keira, Fan Jian-Bing, Grocock Russell, Humphray Sean, Kingsbury Zoya, Peden John, Chien Jeremy, Swisher Elizabeth M, Hartmann Lynn C, Kalli Kimberly R, Goode Ellen L, Sicotte Hugues, Kaufmann Scott H, Harris Reuben S

Abstract excerpt

Ovarian cancer is a clinically and molecularly heterogeneous disease. The driving forces behind this variability are unknown. Here, we report wide variation in the expression of the DNA cytosine deaminase APOBEC3B, with elevated expression in the majority of ovarian cancer cell lines (three SDs a...

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Identifiers

PMID: 24154874
DOI: 10.1158/0008-5472.CAN-13-1753
PMCID: PMC3867573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24154874-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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