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Comprehensive Analyses Identify APOBEC3A as a Genomic Instability-Associated Immune Prognostic Biomarker in Ovarian Cancer.

Frontiers in immunology - 1 Jan 2021

Xu Fangfang, Liu Tingwei, Zhou Zhuonan, Zou Chang, Xu Shaohua

Abstract excerpt

Ovarian cancer (OC) is one of the most malignant tumors whose mortality rate ranks first in gynecological tumors. Although immunotherapy sheds new light on clinical treatments, the low response still restricts its clinical use because of the unique characteristics of OC such as immunosuppressive microenvironment and unstable genomes. Further exploration on determining an efficient biomarker to predict the...

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B7-H1 Antigen
Cell Survival
Cytidine Deaminase
DNA Damage
Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovarian Neoplasms

Tumor Microenvironment

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PMID: 34745121
DOI: 10.3389/fimmu.2021.749369
PMCID: PMC8568129

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