Article
Genetic attributes of blood-derived subtype-C HIV-1 tat and env in India and neurocognitive function.
Journal of medical virology - 1 Jan 2014
Tilghman Myres W, Bhattacharya Jayanta, Deshpande Suprit, Ghate Manisha, Espitia Stephen, Grant Igor, Marcotte Thomas D, Smith Davey, Mehendale Sanjay
Abstract excerpt
Genetic elements in HIV-1 subtype B tat and env are associated with neurotoxicity yet less is known about other subtypes. HIV-1 subtype C tat and env sequences were analyzed to determine viral genetic elements associated with neurocognitive impairment in a large Indian cohort. Population-based sequences of HIV-1 tat (exon 1) and env (C2-V3 coding region) were generated from blood plasma of HIV-infected patients...
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