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Infectious Bronchitis Virus Generates Spherules from Zippered Endoplasmic Reticulum Membranes

23 Oct 2013

Abstract excerpt

UNLABELLED: Replication of positive-sense RNA viruses is associated with the rearrangement of cellular membranes. Previous work on the infection of tissue culture cell lines with the betacoronaviruses mouse hepatitis virus and severe acute respiratory syndrome coronavirus (SARS-CoV) showed that they generate double-membrane vesicles (DMVs) and convoluted membranes as part of a reticular membrane network. Here we...

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PMID: 24149513
DOI: 10.1128/mbio.00801-13

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