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Article

Reovirus Forms Neo-Organelles for Progeny Particle Assembly within Reorganized Cell Membranes

19 Feb 2014

Abstract excerpt

UNLABELLED: Most viruses that replicate in the cytoplasm of host cells form neo-organelles that serve as sites of viral genome replication and particle assembly. These highly specialized structures concentrate viral replication proteins and nucleic acids, prevent the activation of cell-intrinsic defenses, and coordinate the release of progeny particles. Despite the importance of inclusion complexes in viral...

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PMID: 24549844
DOI: 10.1128/mbio.00931-13

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