Article
Association of GRM7 variants with different phenotype patterns of age-related hearing impairment in an elderly male Han Chinese population.
PloS one - 1 Jan 2013
Luo Huajie, Yang Tao, Jin Xiaojie, Pang Xiuhong, Li Jiping, Chai Yongchuan, Li Lei, Zhang Yi, Zhang Luping, Zhang Zhihua, Wu Wenjing, Zhang Qin, Hu Xianting, Sun Jingwen, Jiang Xuemei, Fan Zhuping, Huang Zhiwu, Wu Hao
Abstract excerpt
Several single nucleotide polymorphisms (SNPs) of the Glutamate metabotrophic receptor 7 gene (GRM7) have recently been identified by the genome-wide association study (GWAS) as potentially playing a role in susceptibility to age-related hearing impairment (ARHI), however this has not been validated in the Han Chinese population. The aim of this study was to determine if these SNPs are also associated with ARHI...
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