Article
Genome-wide association study identifies 7q11.22 and 7q36.3 associated with noise-induced hearing loss among Chinese population.
Journal of cellular and molecular medicine - 1 Jan 2021
Niu Yuguang, Xie Chengyong, Du Zhenhua, Zeng Jifeng, Chen Hongxia, Jin Liang, Zhang Qing, Yu Huiying, Wang Yahui, Ping Jie, Yang Chenning, Liu Xinyi, Li Yuanfeng, Zhou Gangqiao
Abstract excerpt
Noise-induced hearing loss (NIHL) seriously affects the life quality of humans and causes huge economic losses to society. To identify novel genetic loci involved in NIHL, we conducted a genome-wide association study (GWAS) for this symptom in Chinese populations. GWAS scan was performed in 89 NIHL subjects (cases) and 209 subjects with normal hearing who have been exposed to a similar noise environment...
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