Article
Genetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcome.
Clinical chemistry - 1 Jan 2014
Meng Qing H, Xu Enping, Hildebrandt Michelle A T, Liang Dong, Lu Karen, Ye Yuanqing, Wagar Elizabeth A, Wu Xifeng
Abstract excerpt
BACKGROUND: The fibroblast growth factor (FGF) and FGF receptor (FGFR) axis plays a critical role in tumorigenesis, but little is known of its influence in ovarian cancer. We sought to determine the association of genetic variants in the FGF pathway with risk, therapeutic response, and survival of patients with ovarian cancer. METHODS: We matched 339 non-Hispanic white ovarian cancer cases with 349 healthy...
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