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Article

Designer cells for stereocomplementary de novo enzymatic cascade reactions based on laboratory evolution.

Chemical communications (Cambridge, England) - 4 Dec 2013

Agudo Rubén, Reetz Manfred T

Abstract excerpt

Designer cells for a synthetic cascade reaction harnessing selective redox reactions were devised, featuring two successive regioselective P450-catalyzed CH-activating oxidations of 1-cyclohexene carboxylic acid methyl ester followed by stereoselective olefin-reduction catalysed by (R)- or (S)-selective mutants of an enoate reductase.

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Identifiers

PMID: 24135920
DOI: 10.1039/c3cc46229c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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