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Article

Laboratory evolution of robust and enantioselective Baeyer-Villiger monooxygenases for asymmetric catalysis.

Journal of the American Chemical Society - 28 Oct 2009

Reetz Manfred T, Wu Sheng

Abstract excerpt

The Baeyer-Villiger Monooxygenase, Phenylacetone Monooxygenase (PAMO), recently discovered by Fraaije, Janssen, and co-workers, is unusually thermostable, which makes it a promising candidate for catalyzing enantioselective Baeyer-Villiger reactions in organic chemistry. Unfortunately, however, its substrate scope is very limited, reasonable reaction rates being observed essentially only with phenylacetone and...

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PMID: 19807086
DOI: 10.1021/ja906212k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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